Cryosurgery is a method used to treat skin lesions. Benign lesions benefit from this therapy: especially seborrheic keratoses, cysts, myxoid, keloids, warts and lentigo. Cryosurgery uses alien agents – easy to apply. Usually no anesthesia is required, but sometimes the dermatologist chose to do a local anesthesia. The agents used in cryotherapy won’t let you scars, so you can stay chill from this point of view. Cryosurgery or cryotherapy as is also called, is one of the seborrheic keratosis removal options that don’t leave scars.
The most common agents used in cryosurgery are: freon, monocloetan, liquid carbon dioxide, liquid nitrous oxide and not last liquid nitrogen.
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The principle of cryosurgery
The skin has a rich capillary network and is relatively resistant to chilling. Applying liquid nitrogen, repeated 4 periods of 60 seconds down to 2 millimeters of the surface temperature to – 11 degrees Celsius. Direct application of liquid nitrogen spray, a time equal lowers temperature – 125 degrees Celsius at a depth of 2 millimeters and – 70 degrees Celsius to 5 mm. Such temperature be reached for cryosurgery skin cancer.
Cryosurgery is more effective when present repeated cycles of cooling – defrost. It finds a greater tissue destruction than one refrigeration. A rapid cooling followed by slow thawing cause maximum damage. Cell survival rate is even lower by as refrigeration speed is higher and lower freezing rate.
More about cryosurgery
The following changes occur in tissues that are acted upon:
- ice crystals form intracellular and extracellular.
- is established cellular dehydration and intracellular ion concentrations increase.
- thermal shock that occurs when the temperature drops below 0 degrees Celsius brutal.
- vascular stasis and tissue necrosis.
- distortion of cell membranes.
Chilling with liquid nitrogen is accompanied by pain that gets worse during defrost.
In the first minutes after the freezing response appears local erythema, papule formation of the appearance of inflammation neighborhood. After a few hours (3-6) shows intense swelling and blistering that regress after two – three days and disappear after 2-4 weeks. epiteilizarea initiated within 3 days after refrigeration.
Melanocytes begin to die at temperatures between – 3 ° C and – 14 degrees Celsius. Melanocytes are more sensitive to cold than seborrheic keratoses for example.
Cryosugery have adverse reactions:
Cryosurgery can cause nerve lesions. Special attention should be given to regions in which nerve fibers are located superficially eg lateral sides of the fingers. Usually the loss of sensitivity is temporary. After applying cryogenic agent lesions require no dressing. It forms a blistering can be large or hemorrhagic. In some cases blistering can decompress using a sterile blade or needle. The treated patient should be reviewed after two weeks.
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